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 Post subject: Abz from NorCal
PostPosted: Sat Nov 21, 2020 4:22 am 
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Hopefully all you dirt treaders are safe and having a grand time down South.
Here in the Bay Area things are good. Before you guys ask me what I'm cooking, I'll tell you.
Image

Image
We have been working on a covid-19 treatment, not vaccine, but treatment. Our drug is nebulized and delivered to the lungs, and used as a treatment on infected patients. So I have been super busy making a stable formulation of our drug product and haven't had much time to ride or edit videos. Finally got an edit done from riding out here in Martinez CA.
Enjoy



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 Post subject: Re: Abz from NorCal
PostPosted: Sat Nov 21, 2020 7:18 pm 
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what's the autoclave for?


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 Post subject: Re: Abz from NorCal
PostPosted: Sat Nov 21, 2020 9:49 pm 
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Ld00d wrote:
what's the autoclave for?


I see what you did there.

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 Post subject: Re: Abz from NorCal
PostPosted: Sat Nov 21, 2020 10:03 pm 
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Thanks to you and your team for working on a treatment that makes sense (therapeutic) instead of some half cocked, raced to market vaccine. (not posting this as a debate, just as a compliment to your team initiative).

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 Post subject: Re: Abz from NorCal
PostPosted: Sat Nov 21, 2020 11:34 pm 
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Abzillah!! Welcome back. Nice looking trail vid, but where’s da yellow thang?!

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 Post subject: Re: Abz from NorCal
PostPosted: Tue Nov 24, 2020 1:40 pm 
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OldDogDan wrote:
Abzillah!! Welcome back. Nice looking trail vid, but where’s da yellow thang?!


I will have to dig up that photo to use, next time.
Some of you guys need to come up here to San Jose and visit, and I'll show you around on Santa Cruz trails. We have an extra bedroom for anyone that wants to visit, bring your wife too if that's the only to make a trip up happen.

oldskool wrote:
Thanks to you and your team for working on a treatment that makes sense (therapeutic) instead of some half cocked, raced to market vaccine. (not posting this as a debate, just as a compliment to your team initiative).


Thank you, and yes, safety is always our number one goal. The rules and regulations for drug products and vaccines are crazy. Even products that are rushed onto the market due to this current situation will be relatively safe. It may not be the best we could do in terms of potency, but safety is always the number one goal. For example, our drug product will require extra safety testing because we have some stabilizing sugars that have not been used with nebulizing delivery method. So our options are to do extra testing to show safety, or change the formulation. The stabilizing sugars will have no negative health affects; because it hasn't been used this way before, we have to do more safety testing. These same stabilizing sugars okay for injectables, because it's been tested with injectables before by other companies.

Ld00d wrote:
what's the autoclave for?


You don't even see an autoclave in the photo! :P


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 Post subject: Re: Abz from NorCal
PostPosted: Tue Nov 24, 2020 5:57 pm 
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Cool trail. Beautiful landscape/scenery. What's the song? Love the applause at the end.

As a fellow pre-clinical drug discovery scientist, I think the below corrections are apt, especially considering the amount of dis/mis-information surrounding 'pharma', COVID, vaccines, etc. Sorry, sometimes I can't turn 'it' off. Imagine you can take the criticism... Edits in bold.

abzillah wrote:
Thank you, and yes, safety is always our number one goal. The rules and regulations for drug products and vaccines are stringent yet, ethically necessary. Even products that are rushed onto the market due to this current situation will be relatively safe. It may not be the best we could do in terms of potency, but safety is always the number one goal. For example, our drug product will require appropriate safety testing because we have some stabilizing sugars that have not been used with nebulizing delivery method. So we need to demonstrate safety, or change the formulation. The stabilizing sugars will likely not have negative health affects; but because it hasn't been used this way before, we have to do standard safety testing. These same stabilizing sugars okay for injectables, because it's been tested with injectables before by other companies.

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 Post subject: Re: Abz from NorCal
PostPosted: Thu Nov 26, 2020 12:29 am 
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ajdonner wrote:
Cool trail. Beautiful landscape/scenery. What's the song? Love the applause at the end.

As a fellow pre-clinical drug discovery scientist, I think the below corrections are apt, especially considering the amount of dis/mis-information surrounding 'pharma', COVID, vaccines, etc. Sorry, sometimes I can't turn 'it' off. Imagine you can take the criticism... Edits in bold.





Thank you for fixing that for me, and happy Thanksgiving everyone!


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 Post subject: Re: Abz from NorCal
PostPosted: Wed Jun 28, 2023 6:57 pm 
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might take a minute to make the connection…

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